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        AnimalTFDB predicted three kinds of factors that involve in transcription process including transcription factors (TFs), transcription co-factors and chromatin remodeling factors. According to the conserved DNA-binding domain (DBD), the TFs were classified into 71 families and a class named "Others" which includes some orphan TFs. Among them, the DBD 3D structures of 60 families have been demonstrated and we used those 3D images as logos for families. For the other 12 families whose 3D structures are unknown, we just put a blank picture on the family position. In addition, we merged the 72 families into 6 groups according to TRANSFAC database and huge literature work. The detailed relations between families and groups were showed on the left treeview. Transcription co-factors and chromatin remodeling factors were gotten by the GO items and were not classified into different families because they didn't have conserved protein domains.


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  • • Transcription factor family



AF-4

Androgen
receptor

AP-2

ARID

bHLH

C/EBP

CBF

CG-1

COE

COUP

CP2

CSD

CSL

CTF/NFI

CUT

DM

E2F

Ecdystd
receptor

ETS

Fork
head

GCM

GCR

GTF2I

HMG

HMGI
HMGY

Homeobox

HSF

HTH

IRF

MBD

MH1

MYB

NDT80/PhoG

NF-YA

NF-YB/C

Nrf1

Nuclear
orphan
receptor

Oestrogen
receptor

Other
nuclear
receptor

Others

P53

PAX

PC4

POU

PPAR
receptor

Progesterone
receptor

Prox1

Retinoic
acid
receptor

RFX

RHD

ROR
receptor

Runt

SAND

SRF

STAT

T-box

TEA

TF_bZIP

TF_Otx

THAP

Thyroid
hormone
receptor

TSC22

Tub

ZBTB

zf-BED

zf-C2H2

zf-C2HC

zf-GAGA

zf-GATA

zf-LITAF-like

zf-MIZ

zf-NF-X1