Coronary artery disease (CAD) or coronary heart disease (CHD) is the leading cause of death worldwide and it is a complex disease influenced by multiple combinations of gene-gene and gene-environment interactions. Until now, many genomic regions and many variants in many genes were implicated as markers of greater susceptibility to develop CAD. To provide a useful and comprehensive gene resource of CAD, we constructed the Coronary Artery Disease Gene Database (CADgene) that was published in the 2011 NAR database issue.
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|Endothelial integrity||Gender difference||Homocysteine metabolism||Immune and inflammation||Lipid and lipoprotein metabolism||Metalloproteinase and ECM|
|Oxidation-reduction state||Rennin-angiotensin system||Glucose metabolism||Thrombosis||Vascular smooth muscle cell abnormalities||Others|
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Publication for more information and for citing this work:
CADgene: a comprehensive database for coronary artery disease genes
Hui Liu; Wei Liu; Yifang Liao; Long Cheng; Qian Liu; Xiang Ren; Lisong Shi; Xin Tu; Qing Kenneth Wang*; An-Yuan Guo*
Nucleic Acids Research 2010; doi: 10.1093/nar/gkq1106
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